Dominique Pinon (Lucien), Alexis Michalik (Georges Feydeau), Simon Abkarian (Ange Fleury), Olivier Gourmet (Constant Coquelin), Blandine Bellavoir (Suzon), Mathilde Seigner (Maria Legault), Guillaume Bouchède (Le Bret), Antoine Duléry (L'Arrogante), Alice de Lencquesaing (Rosemonde Gérard), Thomas Solivéres (Edmond Rostand), Clémentine Célarié (Sarah Bernhardt)

Bill Murray, Adam Driver, Chloë Sevigny, Tilda Swinto, Selena Gomez, Iggy Pop, Steve Buscemi, Danny Glover, Tom Waits, Caleb Landry Jones, Austin Butler

Jacopo Cullin (Agente Kevin/Gavino Zoccheddu), Francesco Pannofino (Dino), Stefano Fresi (Pino), Benito Urg (Badore), Ángela Molina (Teresa), Lazar Ristovski (Taneddu)

Alessandro Borghi (Stefano Cucchi), Jasmine Trinca (Ilaria Cucchi), Max Tortora (Giovanni Cucchi), Milvia Marigliano (Rita Cucchi)

Pierfrancesco Favino (Tommaso Buscetta), Luigi Lo Cascio (Totuccio Contorno), Fausto Russo Alesi (Giovanni Falcone), Maria Fernanda Cândido (Cristina), la moglie di Buscetta, Bebo Storti, Alessio Praticò, Marco Gambino, Goffredo Maria Bruno, Federica Butera, Aurora Peres, Fabrizio Ferracane (Pippo Calò)

Luna Wedler (Mia), Zoë Pastelle Holthuizen (Gianna), Regula Grauwiller (Gabriela), Georg Scharegg (Michael)

Taron Egerton (Elton John), Jamie Bell (Bernie Taupin)

Alicia Vikander (voce narrante)

Eleonora Conti (Maria/ZEN), Susanna Acchiardi (Vanessa), Fabrizia Sacchi (Sandra), Edoardo Lomazzi (Coach Galli), Ruben Nativi (Luca), Alexandra Gaspar (Giada), Maurizio Stefanelli (Dario), Marco Manfredi (Agente Bernini), Giulia Lorenzelli (Professoressa)

Viggo Mortensen (Tony Lip), Mahershala Ali (Don Shirley), Linda Cardellini (Dolores), Sebastian Maniscalco (Johnny Venere), P.J. Byrne (Discografico), Don Stark (Jules Podell), Brian Stepanek (Graham Kindell), Daniel Greene (Poliziotto), Iqbal Theba (Amit), Martin Bats Bradford (Ragazzo dell'autobus), Tom Virtue (Morgan Anderson), Anthony Mangano (Danny), Craig DiFrancia (Dominic), Frank Vallelonga (Rudy Vallelonga)

Alicia Vikander (Danielle Flinders), James McAvoy (James More), Charlotte Rampling (Alma), Alexander Siddig (Dott. Shadid), Reda Kateb (Saif), Jannik Schümann (Paul), Godehard Giese (Wolfgang), Audrey Quoturi (Annie), Celyn Jones (Thumbs), Jess Liaudin (Marcel), Mohamed Hakeem (Amir Yousuf Al-Afghani), Harvey Friedman

Alex Honnold
Tommy Caldwell
Jimmy Chin
Cheyne Lempe
Mikey Schaefer
Sanni McCandless
Dierdre Wolownick
Peter Croft

Casey Affleck (John Hunt), Robert Redford (Forrest Tucker), Sissy Spacek (Jewel), Tom Waits, Danny Glover, Elisabeth Moss, Keith Carradine, Tika Sumpter, Isiah Whitlock Jr., Augustine Frizzell, Gene Jones, Barlow Jacobs, Robert Longstreet

Zain Al Rafeea (Zain), Yordanos Shiferaw (Rahil), Boluwatife Treasure Bankole (Yonas), Kawthar Al Haddad (Souad), Fadi Kamel Youssef (Selim), Haita Izam (Sahar), Alaa Chouchnieh (Aspro), Nadine Labaki (Nadine)

Mel Gibson (Professor James Murray), Sean Penn (Professor William Chester), Natalie Dormer (Eliza Merrett), Eddie Marsan (Mr. Muncie), Jennifer Ehle (Ada Murray), Steve Coogan (Frederick Furnivall), Stephen Dillane (Richard Brayn), Ioan Gruffudd (Henry Bradley), Jeremy Irvine (Charles Hall), Laurence Fox (Phili Lyttelton Gell), Anthony Andrews (Benjamin Jowett), Lars Brygmann (Max Mueller), Bryan Murray (Henry Liddell), David O'Hara (Church), Sean Duggan (Coleman), Olivia Mckevitt (Clare Merrett), Emily Daly (Iris Merrett), Luke Harman (Jack Merrett), Teegan Devlin (Peggy Merrett)

Yalitza Aparicio (Cleo), Marina de Tavira (Signora Sofía), Diego Cortina Autrey (Toño), Carlos Peralta (Paco), Marco Graf (Pepe), Daniela Demesa  (Sofi), Nancy García García (Adela), Verónica García (Signora Teresa), Andy Cortés (Ignacio), Fernando Grediaga (Signor Antonio), Jorge Antonio Guerrero (Fermín), José Manuel Guerrero Mendoza (Ramón), Latin Lover (Professor Zovek), Zarela Lizbeth Chinolla Arellano (Velez), José Luis López Gómez (Pediatra)